The name of the Mantagailiškis Estate originates from the noble Montigail family, which is mentioned in the Biržai region from the 16th century. The estate’s history is evidenced by archaeological research, which uncovered 16th-century stove tile fragments depicting a horse and parts of 17th-century heraldic tiles belonging to Ludwika Karolina Radziwiłł, as well as tiles inscribed with “1645.”
In the latter half of the 18th century, the estate belonged to the Kušelevski family. Sources from 1828 indicate that the landowner of the Padaičių Estate, Karolis Holštenas, married Konstancija Kušelevska from the Mantagailiškis Estate. After 1837, when the vice-marshall of Vilkmergė, Ignatius Kušelevski, passed away, the estate was transferred to the Holšten family in 1840.
In the mid-19th century, the estate underwent reconstruction: Classicist-style palaces, new estate buildings, and a brick fence were constructed. The estate grounds were transformed into a landscaped park with
ponds. Until the early 20th century, the estate was continuously improved—around 1890, Josef Holštenas built a wooden house in the old palace for his son Henrik and his wife Michalina.
During the period of independent Lithuania, with the commencement of estate parcelling, in 1924, Baroness Bronislava Holšten sold part of the estate land and the palace to Juozas Dučinskas, who moved there with his family around 1933. During the Soviet era, following the death of Baroness B. Holšten in 1947 and J. Dučinskas’s deportation to Siberia in 1949, the estate was converted into a production center. In 1994, fragments of the Mantagailiškis Estate with the abandoned palace were returned to the Dučinskas heirs.
In 2007, new owners acquired the estate, and under the initiative of Sigitas Kalkys, extensive archaeological research, palace restoration, and park renovation are being carried out. The estate also hosts tournaments for the patented game "Monteball," named in honor of the estate.