The Evangelical Reformed parish in Biržai was founded by Mikołaj Radziwiłł the Red (1512-1584), and his son, Krzysztof Radziwiłł the Thunderbolt (1547-1603), funded the construction of the church. This church was first mentioned in historical sources in 1584. In 1704, it was destroyed by fire, but a new wooden church was built on its site by 1705. In 1862, this church was demolished, and temporary prayer houses were erected in its place.
Following the design of Riga architect Heinrich Scheel, construction of a Neo-Gothic style church began in 1867, funded by the parishioners of Biržai, and was completed in 1874. This
church reflects the Radziwiłłs, who were significant supporters and promoters of the Reformation. The church became a center of the Reformation in Northern Lithuania.
The church features a unique Neo-Gothic interior, including wooden pews, a large organ loft with an organ, and a pulpit. The interior was completed in 1874, and a rectory was built near the church at the end of the 19th century.
The church is open to visitors on Sundays from 10 AM to 2 PM (from mid-May to early September). At other times, visits can be arranged by phone, with a guide available for tours in Lithuanian, Polish, Russian, and English.